HMGB1 and respiratory failure: Patients with respiratory failure showed trend of increase in HMGB1 [plasma concentration, median(IQR), 3.5(2.1–5.2) vs 3.2(1.7–4.5); 10th–90th percentile, 1.6–13.5 vs 1.0–6.0 ng/mL; gene expression RQ, 1.4(0.9–3.1) vs 1.0(0.6–3.0)].