ERBB2 and ductal breast carcinoma in situ: 005), and age < 40 years (HR: 2.8, p = 0.02) and for mastectomy: HER2 positive (HR: 9.5, p = 0.03), DCIS (HR: 2.7, p = 0.01), No-pCR (HR: 11.4, p = 0.01), and age < 40 years (HR: 2.8, p = 0.006).