For SAS cells, the gene expression of MMP2, MMP9 and MMP14 in ALG-CS was significantly higher than that in ALG (for MMP2 P = 0, for MMP9 P = 0.04634, for MMP14 P = 0.00194), which indicated that ALG-CS could further enhance MMP gene expression in tumor cells compared with ALG. Here, MMP2 is linked to neoplasm.