EED and acute leukemia: During a 1-year observation period, 8 of 10 MOL4070A-infected Eed heterozygotes (Eed+/Δ + MOL4070A) developed acute leukemia, whereas only 1 of 15 MOL4070A-infected controls (Ctrl + MOL4070A) exhibited hematopoietic abnormalities (Fig. 6A, p < 0.01).