Homer1 is a major scaffold protein of the PSD, which is known to have a role in the regulation of dendritic spine morphology and synaptic function in hippocampal neurons.38 To assess protein levels of Homer1 in the CA1 region in schizophrenia, the two main splice variants of Homer1 were measured using antibodies specific for Homer1a (short isoforms, an early immediate gene which acts as a dominant negative for the Homer1 long isoforms) and Homer1b/c (long isoforms, which are expressed constitutively). Here, HOMER1 is linked to schizophrenia.