Apart from AD, CX3CL1/CX3CR1 is also involved in other neuroinflammation disorders, including Parkinson's Disease (PD) [71, 72], multiple sclerosis (MS) [73], tauopathies [33], and age-related macular degeneration (ARMD) [74]. The gene discussed is CX3CR1; the disease is age-related macular degeneration.