Furthermore, compared with normal tissues (n = 6, Figure 1(c)), we have found that PTGR1 is observably upregulated in Garber et al.'s study that analyzed three different NSCLC histological subtypes: large cell lung carcinoma (LCC, n = 4, p = 0.017), ADC (n = 42, p = 1.17E − 4), and squamous cell lung carcinoma (SCC, n = 16, p = 3.56E − 5). This evidence concerns the gene PTGR1 and lung large cell carcinoma.