ANXA5 and cancer: In this study the ex vivo influence of a newly, in silico-designed potential anti-cancer compound namely 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16) was assessed on morphology of participants’ platelets and ESE-16’s possible apoptotic- and autophagic effect by means of flow cytometry through measurement of annexin V-FITC, caspase 3 activity, autophagy-related protein 5 levels and light chain 3-I to light chain 3-II conversion.