However, in the setting of positive serum RPR and CSF leukocytosis and titers positive for VDRL confirmed the diagnosis of syphilitic uveitis, and other infectious and rheumatologic etiologies were concurrently excluded.7,8,15,16 The differential at the time of presentation included but was not limited to the following: Lyme disease, sarcoidosis, tuberculosis (TB), toxoplasmosis, toxocariasis, bartonella, brucellosis, herpes simplex virus, inflammatory bowel disease and rheumatologic conditions such as juvenile idiopathic arthritis and human leukocyte antigen (HLA)-B27-associated disease. Here, MRAP is linked to Lyme disease.