MGMT and neoplasm: In the multivariate model that included KPS, tumor localization, MGMT promoter status, surgical resection status, temozolomide therapy, Dmean IL SVZ ≥ 40 Gy, and Dmean CL SVZ ≥ 30 Gy, average CL SVZ dose higher than 30 Gy remained a prognostic factor for PFS.