Moreover, AT2R stimulation in vitro inhibited apoptosis of cardiomyocytes. In vivo AT2R stimulation led to an increased c-kit+AT2R+ cell population in the infarcted myocardium and reduced apoptosis of cardiomyocytes in rats with acute myocardial infarction [16]. The gene discussed is KIT; the disease is acute myocardial infarction.