MFGE8 and diabetes mellitus: Although it is still required to investigate the molecular and cellular mechanisms by which MFG-E8 expression is upregulated in this disease condition, this study suggests that MFG-E8 plays an important role in atherosclerosis in patients with type 2 diabetes mellitus and that targeting MFG-E8 could be a therapeutic approach for the treatment of atherosclerosis in type 2 diabetes mellitus.