However, no obvious upregulation of TP53 and TRIAP1 was observed after LMP1 overexpression in NPC cells (S10B Fig), suggesting that TRIAP1 is not regulated though LMP1/TP53 pathway in NPC and there may be other regulatory mechanisms involved in TRIAP1 overexpression. The gene discussed is TRIAP1; the disease is nasopharyngeal carcinoma.