In another study focusing on IgA vasculitis,[23] factors associated with relapse were older age, persistent rash, abdominal pain, hematuria, underlying disease at the onset of IgA vasculitis, severity of the leukocytoclasis, and the absence of IgM deposit on the vessel walls.[23] In the study of Alalwani et al,[24] the authors investigated the prognostic value of the type of Ig deposits (IgA, IgG, and IgM) in 218 LCV patients, and demonstrated that IgA (but not IgM and IgG) deposits were associated with a higher risk of renal and gastrointestinal organ involvement. The gene discussed is CD40LG; the disease is Henoch-Schoenlein purpura.