The LH level was suppressed after a 6-day Utrogestan treatment, and no premature LH surge was observed during COH in normal-ovulatory women.[11,12] In PCOS patients, the pituitary LH levels were suppressed in most patients; however, in 13 women, it surpassed 10 IU/L on MC9–11 and decreased subsequently. This evidence concerns the gene PLOD1 and polycystic ovary syndrome.