Epithelial proliferation leading to regeneration and repair is critical for tissue healing following various forms of tissue diseases including liver damage and renal reperfusion injury.[47] [48] EpCAM is also up regulated during inflammatory responses.[17] In the present study, the level of EVs expressing CD326 was increased in patients in the stroke control group as well as in patients with cancer-related stroke. The gene discussed is EPCAM; the disease is stroke disorder.