The decreased expressions of mRNAs in CUMS-induced depression mice include Slc6a11, Hap1, Gad1, Gad2, Gng4, Slc32a1, Doc2g, Slc32a1, Magel2, Prkcd, Ngfr, Dusp1, Th, Itih3, Cacna2d2, Arc, Mbp, Peg10, Fos, and so on. Here, ITIH3 is linked to depressive disorder.