Notably we did neither observe differences in percentual composition of the Ig isotypes, nor in the quantity (IgG1 MFI 3976 ±661; IgG2a MFI 7039 ±1011; IgG2b MFI 3533 ±479; IgM MFI 6180 ±1940) (S6 Fig) between the tumour-bearing mice in the different treatment groups. This evidence concerns the gene CD40LG and neoplasm.