TSHR and Graves disease: Consistent with this, autoantibodies targeting thyroid-stimulating hormone receptor in Graves’ disease cross-react to Yersinia enterocolitica antigens (Brink, 2014, Hargreaves et al., 2013), and activated peripheral blood Tfh cells correlate positively with serum autoantibodies and disease activity/severity in multiple autoimmune diseases (Ueno et al., 2015).