To investigate this, the 8 patients presenting with T1D (red dots, Figure 7B; mean age ± SD, 48 ± 11 years) were compared with an available cohort of 13 patients without T1D but with strong GAD65 reactivity (relative luciferase units > 5) (blue dots, Figure 7B; mean age ± SD, 31 ± 12 years). The gene discussed is GAD2; the disease is type 1 diabetes mellitus.