Primary tumor size (P = 0.023), residual tumor size (P < 0.001), residual node involvement (P < 0.001), MP grades (P = 0.023), vascular invasion (P = 0.027), primary tumor Ki-67 (P < 0.001), residual tumor Ki-67 (P = 0.001), and absolute reduction in Ki-67 (P < 0.001) were significant predictors of RFS and were entered into the multivariate Cox regression model with forward selection. Here, MKI67 is linked to neoplasm.