CD38 and rheumatoid arthritis: We demonstrate a strikingly inhomogeneous distribution of most immune cells and fibroblasts within the sublining layer of both RA and OA tissue with a clear tendency of macrophages (CD68), synovial fibroblasts (CD55), plasma cells (CD38), mast cells (MCT) and endothelial cells (vWF) to accumulate in the upper sublining.