ACE and spindle cell hemangioma: Evaluation of the effect of NO bioavailability on vascular ACE activity after a 6 h incubation period with l-NAME and SNP in aortic tissue from two-month-old SCH revealed that ACE activity was higher in SCH (0.99 ± 0.11 nmol/mg × min, n = 11, p < 0.05) than in age-matched CT hamsters (0.29 ± 0.09 nmol/mg × min, n = 22, p < 0.05; Figure 4).