ACE protein levels in the vasculature of SCH from one to four months of age were evaluated by Western blot as shown in Figure 1B. ACE protein levels were higher in two-month-old (176% ± 19%, p < 0.05, n = 3) than in one-month-old SCH (60% ± 12%, n = 3, p < 0.05). The gene discussed is ACE; the disease is spindle cell hemangioma.