Figure 3A shows that mRNA expression of iNOS was reduced in SCH at all ages tested (40% ± 14% at one month, n = 7, p < 0.05; 40% ± 10% at two months, n = 13, p < 0.05; 42% ± 12% at three months, n = 5, p < 0.05; and 61% ± 12% at four months, n = 7, p < 0.05), when compared to age-matched CT hamsters (100%, n = 11, p < 0.05). This evidence concerns the gene NOS2 and spindle cell hemangioma.