FUS accumulations are a pathological feature in a significant number of ALS/FTD cases, mutations in FUS cause some familial forms of ALS and FTD, and overexpression of wild‐type and ALS/FTD‐mutant FUS induces aggressive disease in transgenic rodents 7, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27. This evidence concerns the gene FUS and amyotrophic lateral sclerosis.