In addition, five of the genes that we identified in this study, CPEB4, DUSP6, NF1, RNF4, and STAT2, were previously proposed as prognostic markers for NSCLC [12, 39], whereas changes in the expression of MCM4 and WEE1 were associated with lung cancer development [33, 41]. This evidence concerns the gene RNF4 and non-small cell lung carcinoma.