NPPB and AL amyloidosis: Increased cardiac troponin indicated disease progression and poor survival in patients with AL amyloidosis, but the role for troponin in the definition of response remains less established.11, 49, 62, 66, 67 Finally, NT-proBNP should continue to be evaluated for use in assessing cardiac response in patients with both mutated and wild-type cardiac transthyretin amyloidosis.