To assess the diagnostic accuracy of autofluorescence for OSCC, lung cancer, esophageal cancer, stomach cancer and colorectal cancer and their PML, Fig. 2 and Supplementary Fig. S2 showed the forest plots of the pooled sensitivity and specificity of the corresponding 24, 25, 12, 9, and 19 studies; moreover, the forest plots of sensitivity and specificity on the use of autofluorescence alone or with algorithms for OSCC and OPMD were also depicted in Supplementary Fig. S3 and S4, respectively. The gene discussed is PML; the disease is lung carcinoma.