Examining tissue and blood samples from patients with different tumors treated with anti‐PD‐1 therapy including NSCLC, PD‐1 expression by TILs was significantly positively correlated with PD‐L1 expression by the tumor cells and immune infiltrate cells, reflecting an immunosuppressive microenvironment 43. This evidence concerns the gene PDCD1 and non-small cell lung carcinoma.