IFNB1 and myeloid sarcoma: Use of DMTs early in the MS disease course has been supported by pharmacoeconomics studies that indicate early vs. delayed treatment with IFN-β, in particular, may be more cost-effective in the long term, as reduction of relapses, hospitalizations, and indirect costs, and gains in quality of life, and appear to outweigh the costs of DMTs [14, 15, 25].