The protein can also be N-glycosylated and ubiquitinated.4, 27, 28, 33, 34, 36, 37 Dysregulation of GPRC5A was also shown to result in abnormal activation of NF-κB signaling and STAT3 signaling.44 Recently, it was also shown that in breast cancer GPRC5A may be involved in DNA repair in cooperation with BRCA1.22 From a post-transcriptional regulation standpoint, however, very little is known. Here, GPRC5A is linked to breast carcinoma.