DCK and cancer: Indeed, previous studies have shown that in pancreatic cells HuR is involved in post-transcriptionally stabilizing the translation of many important proteins.60, 61 Specifically for our context, HuR has been shown to be a key mediator of gemcitabine's efficacy in cancer cells through its stabilization of dCK mRNA.56 We thus hypothesized HuR's involvement in mediating the observed behavior.