In contrast, Blm haploinsufficiency had no impact on tumor development, progression, or regression in a Ccsp/Fgf-10 transgenic model which overexpresses the growth factor Fgf-10 under control of the lung-specific Clara cell secretory protein (Ccsp) promoter (Figure 1(d)) (Boivin & Groden, personal communication). This evidence concerns the gene FGF10 and neoplasm.