The profiles of Hp, M-SAA3 and CRP over time during the S. uberis mastitis challenge are shown in Fig. 2, 3 and 4 respectively with the median value and the individual values shown for the six infected quarters from cows 1, 2, 3, 4, 5, 6 (cow numbers consistent with Tassi et al.4). This evidence concerns the gene HP and mastitis.