From the 552 common upregulated and 550 common downregulated genes in SLE, we only identified three genes (MX1, G protein-coupled receptor 84 (GPR84), E2F transcription factor 2 (E2F2)), which were significantly increased in SLE LN+ compared with both NC and SLE LN− (p < 0.05, Fig. 6). This evidence concerns the gene E2F2 and systemic lupus erythematosus.