In the univariate analysis, age (p = 0.0254), lymph node status (p = 0.0005), tumor grade (G1 vs. G2 + G3) (p = 0.001), adjuvant radiotherapy (p = 0.000005) and p16-overexpression (p = 0.0216) were prognostic factors for OS (Table 2). The gene discussed is CDKN2A; the disease is neoplasm.