Recently, we found that liprin-β1 interacts with KANK1 (van der Vaart et al., 2013), one of the four members of the KANK family of proteins, which were proposed to act as tumor suppressors and regulators of cell polarity and migration through Rho GTPase signaling (Gee et al., 2015; Kakinuma et al., 2008, 2009; Li et al., 2011; Roy et al., 2009). The gene discussed is KANK1; the disease is neoplasm.