Our observations confirm the previous reports of some authors.(2,31,32) We found highplasma ANF levels without a correlation with hyponatremia and natriuresis, as shownby Diringer et al.(2,31,32) Tsubokawa et al.,(33) Yamaki et al.(34) and Hansel et al.(35) These authors also did not find any correlation with ANF,hyponatremia and natriuresis; however, they did not find high plasma ANF levels, aswe observed in our study. Here, NPPA is linked to Hyponatremia.