ERBB2 and breast cancer: A comparable phosphorylation pattern, but modified CREB forms as demonstrated by two bands at ~90 and ~120 kDa were observed in the HER-2/neu+ breast cancer cell line SKBR3 under hypoxic treatment (Supplementary Figure 1C), while the 60 kDa band was neither visible with CREB nor with pCREB antibodies.