As shown in Figure 4, the majority of non-tumor-infiltrating CD3+CD56+ NKT-like cells produced IFN-γ and TNF-α, but in tumors, we observed that significantly lower frequencies of IFN-γ and TNF-α-producing CD3+CD56+ NKT-like cells than those in non-tumor tissues. This evidence concerns the gene IFNG and neoplasm.