Therefore, the objective of this study was to investigate the associations between obesity indicators [BMI and waist circumference (WC)] with FBG, PV, and PSA parameters [PSA serum level, PSA density (PSAD), and PSA increasing rate per year (PSAR)] in Chinese men undergoing physical exam routine screening, ultrasonography, and digital rectal examination (DRE). The gene discussed is KLK3; the disease is Obesity.