MKI67 and hereditary clear cell renal cell carcinoma: However, this information has not been evaluated in renal cell carcinoma to date, apart from a pharmacodynamic study which used FLT PET to assess proliferative changes after sunitinib treatment which showed an increase in cellular proliferation as measured by FLT PET, but not with immunohistochemical analysis of Ki-67 index with pathology specimens (19).