OXT and pulmonary arterial hypertension: For example, the most recently updated PPH treatment guidelines prepared by the World Health Organization state that TA (1 g over 5 minutes, repeated within 30 to 60 minutes if necessary) is recommended for the treatment of PPH if oxytocin and other uterotonics fail to stop bleeding or if it is thought that the bleeding may be partly due to trauma (weak recommendation)25.