STUB1 and metabolic dysfunction-associated steatohepatitis: On the other hand, Oil red O-stained sections revealed “microvesicular” steatosis, but not the macrovesicular steatosis characteristic of clinical NASH and rodent NASH-models7, 11, 27, 28, that progressed from 4 to 9 months in CHIP−/−-mice relative to age-matched CHIP+/+-controls (Fig. 2).