A connection between the Epa proteins and CD43 (leukosialin)/CD45 (receptor-type tyrosine-protein phosphatase C) is also present in the LGI network (Fig. 4), and this is justified by the presence of the T antigen that is linked to leukemia- and HIV-associated CD45 and to WAS-associated CD43, as well as other glycans related to a healthy condition. This evidence concerns the gene SPN and leukemia.