SPOP and neoplasm: As already reported33, other regions from 17q were found to be amplified including the 17q21.32-17q21.33 region that harbours SPOP (amplified in 14% of the tumours) and KAT7 (20%) genes as well as the 17q23.1-17q24.3 region that harbours RPS6KB1 (25%), PPM1D (27%), BCAS3 (20%) and DDX5 (16%) genes.