CDK5 and metastatic malignant neoplasm in the lymph nodes: CDK5 expression in the group with lymph node metastasis (86.5 %) was higher than that in the non-lymph node metastasis group (51.5 %) (P < 0.001) (Fig. 2b), indicating that CDK5 up- regulation may be relative to the carcinogenesis and progression of cervical cancer.