MMP2 and type 1 diabetes mellitus: In our analysis, both C-MSCs and T1D-MSCs presented increased absolute expression of genes encoding cytokines (IL-6, TGF-β1), growth factors (platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), fibroblastic growth factor (FGF), HGF) and MMP-related molecules such as MMP-2, MMP-9, and MT1-MMP (Fig. 6).