Of these, FGF3 and HGF (Fig. 7a), as well as EGFR and FGFR1 (Fig. 7b), were downregulated in T1D-MSCs, while MT1-MMP (MMP14) and MMP2 were upregulated in T1D-MSCs (Fig. 7c), when compared with their healthy counterparts. Here, FGFR1 is linked to type 1 diabetes mellitus.