By day 28 post tumor injection, Gr1+CD11b+ MDSCs constituted 55.3% of the spleen cells in DMSO-treated tumor-bearers, whereas the 25 and 50 mg/kg curcumin treatments reduced the proportion of MDSCs to 34.1% and 17.2%, respectively (Fig. 1B, middle panel). The gene discussed is ITGAM; the disease is neoplasm.