Vessel invasion (P < 0.001), T stage (P < 0.001), lymph node metastasis (P < 0.001), distant metastasis (P = 0.046), TNM stage (P < 0.001), and calpain-9 expression (P < 0.001) were found to be risk factors for survival in patients with gastric cancer (Table 2). Here, CAPN9 is linked to metastatic malignant neoplasm in the lymph nodes.