In terms of the association between clinical phenotype and the NOD2 polymorphism, the rs2066847 variant was found in 15 Crohn’s disease patients with clinical phenotypes B1 (33.3%), B2 (40.1%) and B3 (26.6%), respectively, carrying the heterozygous mutation C_C (Table 2) and in two Crohn’s disease patients carrying the homozygous mutation (both B3). The gene discussed is NOD2; the disease is Crohn disease.