ANGPT2 and major depressive disorder: Only 5 of 33 markers previously found to be associated with MDD in the study by Bot et al.11 were also found to differ between controls and atypical depression in the present study (FABPa, ANG2, CathD, vWF and MIF), the observed directions of effect being consistent with the analysis by Bot et al. Notably, the markers in Bot et al. were derived before FDR correction and FDR adjustment showed that these markers were related to MDD only at a relatively high FDR level (range q-values 0.09–0.30).