MART1 (MELAN-A) and TRP1 or tyrosinase-related protein (gp75) are melanoma antigens expressed both in melanocytes and melanomas24, and MCAM (MUC18, CD146) is a melanoma cell adhesion molecule that is abnormally expressed in a variety of tumors and is closely associated with metastasis25. Here, MLANA is linked to melanoma.